© 2005 - 2019 WebMD LLC. drug and may not reflect the rates observed in clinical practice. weeks). 11% Hispanics, 5% Asians) treated for up to 12 weeks and 576 patients treated Placebo, Regardless of Causality. Serious side effects of ezetimibe include hypersensitivity reactions (including angioedema - swelling of the skin and underlying tissues of the head and neck - that can be life-threatening), skin rash, nausea, pancreatitis, muscle damage (myopathy or rhabdomyolysis), and hepatitis. The most common adverse reactions This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. The frequency of less common adverse reactions was The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Does Zetia (ezetimibe) cause side effects? with Zetia 10 mg/day for a median treatment duration of 12 weeks (range 0 to 39 ≥2% and greater than placebo) in the Zetia monotherapy controlled Getting your cholesterol and triglyceride levels in an optimal range will help protect your heart and blood vessels. Caution should be exercised when using Zetia and cyclosporine concomitantly due to increased exposure to both ezetimibe and cyclosporine. Sign Up to Receive Our Free Coroanvirus Newsletter, Inflammation Of The Tissue Lining The Sinuses, A Condition With Muscle Tissue Breakdown Called Rhabdomyolysis, A Disease With Shrinking And Weaker Muscles Called Myopathy, A Significant Type Of Allergic Reaction Called Anaphylaxis, A Type Of Allergic Reaction Called Angioedema, Erythema Multiforme, A Type Of Allergic Skin Reaction, Inflammation Of The Liver Called Hepatitis. headache; cholelithiasis; cholecystitis. Need to lower your cholesterol levels? Incidence Greater than Statin, Regardless of Causality. WebMD does not provide medical advice, diagnosis or treatment. The most common side effects of Zetia are: Hypersensitivity reactions, including angioedema (swelling of the skin and Incidence rates (95% CI) for clinically important elevations All rights reserved. or added to on-going statin therapy for a median treatment duration of 8 weeks Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts. What drugs interact with Zetia (ezetimibe)? When diet and exercise aren't enough, should you turn to drugs? It can also cause other side effects. placebo-controlled studies of Zetia, regardless of causality assessment, are TABLE 1: Clinical Adverse Reactions Occurring in The following serious adverse reactions are discussed in Ezetimibe is also known by the brand name Ezetrol. varying conditions, adverse reaction rates observed in the clinical studies of Use these smart diet tips to quickly and easily lower your blood cholesterol levels.... High cholesterol can be a dangerous condition. Feeling tired or weak. group of patients treated with Zetia + statin that led to treatment discontinuation Common side effects of ezetimibe include diarrhea, abdominal pain, back pain, joint … groups. High cholesterol and triglyceride levels increase the risk of cardiovascular disease. cholesterol through the veins and arteries of the body. 2396 patients with primary hyperlipidemia (age range 9-86 years, 50% women, 90% for up to an additional 48 weeks evaluated coadministration of Zetia and infection (4.3%), diarrhea (4.1%), arthralgia (3.0%), sinusitis (2.8%), and See additional information. Selected from data included with permission and copyrighted by First Databank, Inc. infrequent events. There are no adequate studies of ezetimibe in pregnant women. ©1996-2020 MedicineNet, Inc. All rights reserved. Cholesterol is naturally produced by the body, and is a building block for cell membranes and hormones. In patients treated with cyclosporine, the potential effects of the increased exposure to ezetimibe from concomitant use should be carefully weighed against the benefits of alterations in lipid levels provided by ezetimibe.