Endocrinological Features of Hartsfield Syndrome in an Adult Patient With a Novel Mutation of FGFR1, The Effect of Sprint Interval Training on Body Composition of Postmenopausal Women, Hypothalamic–Pituitary and Growth Disorders in Survivors of Childhood Cancer, Advances in Allergen Immunotherapy for Asthma, Remote, Non-Physician-Led Care Cuts LDL, BP in High-Risk Patients, Statins Beneficial in Elderly, Guidelines Should Be Strengthened, AACE Issues 'Cookbook' Algorithm to Manage Dyslipidemia, First-of-Its Kind Guideline on Lipid Monitoring in Endocrine Diseases, Women With Heterozygous FH Less Likely to Receive Treatment, Amazon Launches Online Pharmacy in New Contest With Drug Retail, Pharmacotherapy Considerations in Hospitalized Patients With COVID-19 Pneumonia. Nicholls SJ, Brandrup-Wognsen G, Palmer M, Barter PJ. USA.gov. 2007;64(3):276-284. Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. DCI = Deyo-Charlson comorbidity index; ATP III = Adult Treatment Panel III b p < 0.05 for comparison between drugs. All material on this website is protected by copyright, Copyright © 1994-2020 by WebMD LLC. This website also contains material copyrighted by 3rd parties.  |  Both rosuvastatin and atorvastatin … Usefulness of aggressive lipid-lowering therapy with rosuvastatin in hypercholesterolemic patients with concomitant type 2 diabetes. In terms of efficacy there are no significant differences between atorvastatin & rosuvastatin (i.e., the same in terms of efficacy) --- 1st URL 2.  |  Crestor rated 6.0/10 vs Rosuvastatin rated 5.5/10 in overall patient satisfaction. 2008 Dec;15(6):314-23. doi: 10.5551/jat.e567. Little is known about the differences between standard-dose statins effects on glucose level and lipids in Japanese patients with diabetes mellitus (DM). Meta-analysis of comparative efficacy of increasing dose of Atorvastatin versus Rosuvastatin versus Simvastatin on lowering levels of atherogenic lipids (from VOYAGER). filled statin prescriptions, Mean ± S.D. The 1,049 patients were randomly assigned to either the rosuvastatin group or atorvastatin group. [2,5,8,9] The National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP) III has developed evidenced-based treatment guidelines to aid in the management of high cholesterol. Coronary heart disease (CHD) is the most common cause of death in the United States, accounting for nearly 500,000 deaths annually and an estimated $142 billion in annual direct and indirect costs. Please see our, 2001http://www.medscape.com/features/year-in-medicine/public/2014. Crestor rated 6.0/10 vs Lipitor rated 4.8/10 in overall patient satisfaction. Attainment rates for NCEP LDL cholesterol goals were significantly higher in patients receiving rosuvastatin. Vincent J. Willey, Pharm.D., is Vice President, Health Outcomes Research, HealthCore, Inc. Click the topic below to receive emails when new articles are available. Differences between rosuvastatin and atorvastatin in lipid-lowering action and effect on glucose metabolism in Japanese hypercholesterolemic patients with concurrent diabetes. Get the latest public health information from CDC: https://www.coronavirus.gov. aLDL = low-density-lipoprotein, HDL = high-density-lipoprotein. LDL = low-density-lipoprotein; CHD = coronary heart disease; CVD = cardiovascular disease; DM = diabetes mellitus; ACS = acute coronary syndrome; MS = metabolic syndrome. [3] These guidelines are based on results from previous randomized clinical trials and include specific goals for LDL cholesterol. eAdjusted for age, sex, baseline laboratory values, duration of therapy, and National Cholesterol Education Program risk status. eCollection 2017 Nov. Angelidi AM, Stambolliu E, Adamopoulou KI, Kousoulis AA. Since cholesterol synthesis peaks between midnight and 2 am, simvastatin, pravastatin, fluvastatin, and pitavastatin have a shorter half-life and should be taken at bedtime. 2017 Apr 30;12(1):39-40. eCollection 2017. Rosuvastatin 5 mg and atorvastatin 10 mg have a similar lowering effect on non-HDL-C, but might be different in terms of adverse effect on glucose levels. Commenting is limited to medical professionals. Compare Crestor vs Rosuvastatin head-to-head with other drugs for uses, ratings, cost, side effects and interactions. eCollection 2018. Kameda A, Nakamura A, Kondo Y, Kimura M, Terauchi Y. Diabetol Int. Conclusions: Comparative study of low doses of rosuvastatin and atorvastatin on lipid and glycemic control in patients with metabolic syndrome and hypercholesterolemia. No significant differences were found in HDL cholesterol and triglyceride levels between groups. After adjusting for baseline differences between groups, patients receiving rosuvastatin had significantly greater mean percent reductions in LDL cholesterol, total cholesterol, and non-high-density-lipoprotein (non-HDL) cholesterol than did patients receiving atorvastatin (p < 0.001 for all comparisons). Additionally, the rosuvastatin group of patients, who were treated with half the dose of atorvastatin, achieved a significantly greater reduction in LDL-C levels (WMD = -3.57; 95% CI: -5.40--1.74 mg/dl, p < 0.001). Epub 2010 Feb 26. 2009 Dec;36(3):412-8. doi: 10.1007/s12020-009-9235-6. Methods: Electronic medical and pharmacy administrative claims from a western U.S. health plan with approximately 8 million covered members were extracted and used in this retrospective, longitudinal cohort study. Statins in hypercholesterolaemia: a dose-specific meta-analysis of lipid changes in randomised, double blind trials. COVID-19 is an emerging, rapidly evolving situation. The mechanism of action of both atorvastatin and rosuvastatin (called statins) is identical. Because research is limited regarding the effect of statins outside of randomized, controlled trials, this study compared the effectiveness of rosuvastatin versus atorvastatin in reducing lipid levels and in attaining LDL cholesterol goals using both the ATP III guidelines alone and in combination with the updated ATP III optional goals in an observational, usual care setting. 2010 Mar;25(1):27-35. doi: 10.3904/kjim.2010.25.1.27. They also helps raise \"good\" cholesterol (HDL) in the blood. And although rosuvastatin … If you log out, you will be required to enter your username and password the next time you visit. Since LDL cholesterol goals differed using the ATP III guidelines alone versus in combination with the updated ATP III optional goals, the number of eligible patients in each of these analyses varied.